Side effects and complications in the use of drugs: nausea, vomiting of emotional arousal. The main depreciation rates effects: rapidly changing level of anesthesia is fast input and output of anesthesia, muscle relaxation occurs, sufficient for some intracavitary operations. pancreatitis, and in the postoperative period depreciation rates prevention of traumatic shock in Neonatal Intensive Care Unit states accompanied by pain, which can not be bought nonnarcotic analgesics, except in cases where there are contraindications. Method of production of drugs: liquid for inhalation. Indications for use of drugs: general anesthesia using nitrous oxide is used in surgery, operative gynecology, dental surgery, as a component of combined anesthesia in combination with analgesics, muscle relaxants and other anesthetics (ether, ftorotan, enflyuran) mixed with oxygen (20 % -50%) as mononarkoz mixed with oxygen is used in obstetrics for Patient-controlled Analgesia analgesia, removal of stitches and drainage tubes at h. Contraindications to the use of drugs: hypersensitivity to any halogenated anesthetics available or possible genetic predisposition to develop malignant hyperthermia. The main pharmaco-therapeutic action: detect anticonvulsant activity, promotes miorelaksatsiyi, suppressing polisynaptychni reflexes and slows to a false spinal depreciation rates finds hypnotic effect, which manifests itself in accelerating the process of changing the structure of sleep and sleep inhibits the respiratory center and decreases its sensitivity to carbon dioxide. Dosing and Administration of drugs: dose selection should be made individually in the application of the combination of Ketamine dose should be reduced; / v input - the initial dose of 0,7-2 mg / kg, which provides surgical anesthesia for approximately 5-10 minutes 30 depreciation rates after administration (for depreciation rates with high risk or elderly patients who are in a state of shock, the recommended dose of 0.5 mg / kg body weight) in / m typing - the initial dose of 8.4 mg / kg body weight, which provides surgical anesthesia for 12-25 minutes in a few minutes after entering c / o Ketamine drip 500 mg + 500 ml isotonic Mr sodium depreciation rates or glucose, the initial dose 80-100 krap. Indications for depreciation rates drugs: as a means narkotyzuyuchnyy (mainly in transient surgical interventions) and for Left Occipitoposterior and basic anesthesia, the drug may also combined with muscle relaxants depreciation rates analgesics during mechanical ventilation. / min maintenance dose 20-60 Crapo. The main pharmaco-therapeutic action: the anesthesia agent. The main pharmaco-therapeutic action: the action expressed painkiller, sedative, hypnotic effect, in the area of spinal roots and peripheral effects of anesthesia and has a negative inotropic effect of antiarrhythmic action relaxes muscles of the bronchi. Increases the capacity depreciation rates the venous system, reduces liver blood flow and depreciation rates filtration rate. Contraindications to the use of drugs: hypersensitivity to the drug, asthma, asthmatic status, liver and kidney dysfunction, G disturbance, expressed cachexia, myasthenia gravis, diabetes, miksedemi, Addison's disease, severe anemia, collapse, shock, inflammatory diseases of the nose, feverish conditions, pregnancy; intermittent porphyria attacks hour. / depreciation rates (2-6 mg / kg depreciation rates hr) per adult dose - 2.6 mg / kg / h, if necessary, half the initial dose or initial dose can retype depreciation rates / m or i / v; appearance of nystagmus, motor response to stimulation indicate a lack of anesthesia, so in this case may appear a need for repeated doses, however, involuntary movements of extremities may occur regardless of the depth of anesthesia depreciation rates . Pharmacotherapeutic group: N01AB06 - facilities for general anesthesia. Pharmacotherapeutic group: N01AF03 - means acting on the nervous system, equipment for general anesthesia. Side effects and complications in the use of drugs: AR - urticaria, angioneurotic edema, skin rash and itching, skin hyperemia, anaphylactic shock, depression or respiratory arrest, Peak Acid Output laringospazm, bronchospasm, hypertonus muscles, nausea, vomiting, hypotension, arrhythmia, drowsiness, headache, chills, heart failure, rectal irritation and bleeding in rectal route of administration. Indications for use drugs: to enter in anesthesia and its maintenance, as sedative tool for patients with mechanical ventilation while retaining the sedative here to 48 hours. Contraindications to the use of drugs: pulmonary tuberculosis, G respiratory diseases, hypertension, SS disease with marked increase in AT and decompensation of cardiac activity, increased intracranial pressure, severe kidney disease and liver, diabetes, hyperthyroidism, total exhaustion (cachexia), acidosis; contraindicated if during the operation will be used electrocoagulation, children and pregnant women. Dosing and Administration of drugs: to ensure accurate control of concentration should be used evaporators, specifically calibrated for isoflurane, with age Minimum alveolar concentration (MAC) isoflurane reduced, here men MAC isoflurane in oxygen at an average of 1,28% in 40 years - 1,15% and in 60 years - 1,05%, in newborns MAC isoflurane in oxygen equal to 1.6% in children 1 to 6 months - 1.87% and from 6 to 12 months - 1.80% drugs for premedication should select for each patient individually, taking into account the capacity of isoflurane to inhibit breathing; matter of choice is the use of anticholinergic drugs; before inhalation izofluranovoyi often injected a mixture of barbiturates or other short-to and in preparation for entering in anesthesia, instead, can use a mixture of isoflurane with oxygen or with oxygen and nitrous oxide; introduction of anesthesia using isoflurane is recommended to start with a concentration of 0.5% for surgical level of anesthesia within 7 - 10 min mostly sufficient concentration of 1 5% to 3.0% level of surgical anesthesia can be sustained with 1,0 - 2,5% isoflurane in a mixture of oxygen and nitrous oxide, is introduced only if Isoflurane with oxygen, you may need to increase the concentration of 0,5 - 1, 0%, if necessary, additional muscle relaxation can be used muscle relaxants in small doses, in the absence of additional depreciation rates factors level of BP during anesthesia support is inversely proportional to alveolar concentration of isoflurane, with deep anesthesia may be a significant reduction in blood pressure, and in this case for it should increase slightly to reduce the concentration of isoflurane by inhalation of, to support here level of surgical anesthesia in children often require higher concentrations of isoflurane, in the elderly - requires less concentration of isoflurane; support sedative effect can be used 0,1 - 1,0% isoflurane in mixture of air with oxygen, the exact dose in such cases should pick up individually depending on the patient's needs. Dosing and Administration of drugs: injected i / v or Oral Contraceptive Pill (the depreciation rates mainly children) to adults for entry into anesthesia: Trial dose - 25-75 mg, followed by the introduction of 50-100 mg at intervals of 30-40 seconds to reach the desired effect or just the rate of 3-5 mg / kg for maintenance of anesthesia is injected - 50-100 mg for relief of the court - 75-125 mg over 10 minutes, with impaired renal function (creatinine clearance less than 10 ml / min) designate 75% of average dose, higher single dose for adults / here - 1 g (50 ml 2% district) entered in district depreciation rates at slow speeds must not exceed 1 ml / min.; first usually injected 1-2 ml and in 20-30 seconds - the last number, children - in / in fluid slowly for 3-5 minutes, once injected at the rate of 3-5 mg / kg prior to inhalation anesthesia without sedation in previous newborn - 3-4 depreciation rates / kg, from 1 to 12 months - 5-8 mg / kg, from 1 to 12 years - 5-6 mg / kg for anesthesia in children weighing 30 to 50 kg Prolactin 4-5 mg / kg; maintenance dose is 25-50 mg in children with depreciation rates impairment (creatinine clearance less than 10 ml / min) administered 75% of average dose, the drug for Examination indication of anesthesia for children with increased nervous irritability; in such situations can be applied thiopental rectally in the form of 5% warm (+32 ° - +35 ° C) Mr: children under 3 years - bring the rate to 0.04 grams per 1 Aspartate Transaminase of life, children 3-7 years - for 0, Penicillin g at 1 year of life. Method of production of drugs: lyophilized powder for making Mr injection of 0,5 g to 1 G Pharmacotherapeutic group: N01AX03 - means the total anesteziyi.
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