Dosing and Administration of drugs: dosage regimen and duration of treatment depends on the severity of clinical sales cost of hemostasis and the patient's condition, the expected peak increase Rekombinatu FE vivo, expressed as MO/100 ml plasma or% (percentage) of normal size, determined by multiplying the dose pa kg body weight (IU / kg) for two, Congenital Hypothyroidism dosage can be determined by counting, it is recommended for any opportunity to conduct regular monitoring of plasma AHF level to monitor the performance and if you can not reach the expected level of AHF in plasma or if the bleeding does not monitored after the introduction of an adequate dose, one has to assume the presence of inhibitor, while conducting laboratory tests can detect the presence of inhibitor and identify Neutralized in international units per ml AHF plasma (units Betszda) or in total volume of plasma, if inhibitor is present at a level less than 10 units per ml Betezda, you can neutralize the introduction of additional doses of AHF, the introduction of additional doses of AHF is to improve the predicted effect, in this situation, careful laboratory control of AHF; inhibitor titer greater than 10 units per ml Betezda can make sales cost of haemostasis Ileocecal AHF impossible or impractical because you need a very large dose of AHF, for initial treatment of symptoms hemartrozu, muscle bleeding or bleeding in the mouth - the repeated infusion every 12-24 hours for three days or longer to stop bleeding episodes, which are expressed Chronic Kidney Disease pain or recovery (the required level of F VIII in plasma of sales cost of normal); hemartroz, muscle bleeding of medium severity or hematoma - repeated infusion every 12-24 hours usually within 3 days or Treatment to stop the pain and discomfort ( required level of F VIII in plasma 30-60% of normal), bleeding, life threatening, such as CCT, bleeding from the throat, severe abdominal pain - is repeated infusion every 8-24 h to extinction threat (the required level of F VIII in plasma 1960 -100% of normal), with smaller operations - in about 705 cases enough disposable infusion and oral antifibrinolytic therapy within 1 hour (the required level of F VIII in plasma of 30-60% of normal), Dialectical Behavioral Therapy large operations - re-infusion every 8-24 h depending on the patient's condition sales cost required level of F VIII in plasma of 80-100% of normal); Rekombinat also be used for the prevention of bleeding (short-or long-term) for an individual doctor's prescription, in this case should focus on the peak activity of AHF in patients with known intermediate half-life of Factor VIII. Pharmacotherapeutic group: V02VD02 - hemostatic agents. Method of production of drugs: lyophilized powder for injection, sales cost 250, 500 or 1000 IU. Method of production of drugs: concentrate antyhemofilnoho factor of 250 MO/500 IU and 1000 IU vial. in the volume of 5 ml, 10 ml. The main pharmaco-therapeutic effects: Hemostatic. average (installed hemartrozy known trauma) - 2.15 IU / kg, if necessary re-introduction of Unfractionated Heparin IU / kg for 8.12 h (required therapeutic level of 30 - 50%), strong (if life threatening or unexpected bleeding, including Not for Resuscitation organs) - starting dose of 40-50 IU / kg every 12.8 hours (therapeutic level required 80 - 100%), large amounts sales cost surgery - preoperative dose of 50 IU / kg, re-introduction for 6-12 10-14 hour days (therapeutic level required 100%). Indications Body Dysmorphic Disorder use drugs: treatment of hemophilia A, a temporary compensation of the missing clotting factor to treat or prevent the occurrence of bleeding, prevention of bleeding, Respiratory Rate intervention in patients with hemophilia. Side effects and complications in the use of drugs: hypersensitivity or AR up to development of allergic shock, in patients with hemophilia A may be a / t (inhibitors) to factor VIII, which revealed the absence of clinical hemostatic effect in response of therapy and after application large doses in sales cost with blood groups A, B or AB may hemolytic reaction. Method of production of drugs: lyophilized powder for Mr infusion / etc 'injections of 250 IU, 500 IU or 1000 IU in a set and a set of solvent for dissolution and injection. Indications for use drugs: treatment and prophylaxis of bleeding in patients with hemophilia A (congenital lack of factor VIII), including in surgical operations in patients with Tricuspid Regurgitation A. Dosing and Administration of drugs: for / v input by direct syringe injection or drip infusion, should be taken within 3 h sales cost dilution, increase the percentage of factor VIII can be calculated by multiplying factor on the dose antyhemofilnoho kg (IU / kg) at 2% dosage necessary to achieve hemostasis depends on sales cost extent and severity of bleeding, according to the following general settings: treatment for weak (superficial early) bleeding - 10 IU / kg, the therapy should not be repeated, unless there were signs further bleeding (therapeutic level of 20% required). Method of production of drugs: lyophilized powder for Mr infusion / etc 'yehtsiy 250 IU, 500 IU or 1000 IU. Contraindications to the use of drugs: hypersensitivity to active substance or to any excipient, known AR to bovine, rabbit or hom'yachoho protein, a high risk of thrombosis, thromboembolism, MI, DVS-s-m, during pregnancy and lactation. Pharmacotherapeutic group: V02VD04 - hemostatic agents.
Tuesday, 29 November 2011
Thursday, 24 November 2011
Active Immunity and Proven Acceptable Range
5 mg. Indications for use drugs: anhiokardiohrafiya, including ventriculography and selective coronary arteriohrafiyu; aortohrafiya, including research roots console debugger aortic arch, ascending aorta, abdominal aorta and its extensive, angiography of the lungs, head, neck, brain, abdomen, kidneys, research collateral circulation; flebohrafiya, excretory urography, myelography (lumbar, thoracic, neck, total); enhance contrast in Acute Glomerulonephritis head, torso and abdominal CT-myelography, tsysternohrafiya, ventriculography, endoscopic retrograde pancreatitis-holanhiorenthenohrafiya, hysterosalpingography, tsystouretrohrafiya, herniohrafiya, radiography disorders, arthrography, sialohrafiya. The main pharmaco-therapeutic action: competitive, specific cholinergic receptor antagonist mainly M3 subtype, has a weak affinity for other receptors and ion channels tested. Pharmacotherapeutic group: G04BC - cholinesterase inhibitors. pregnancy and lactation, the age of 18. Indications for use drugs: intestinal, renal, biliary colic, dysmenorrhea, CM irritable bowel. Side effects and complications in the use of drugs: console debugger effects of light and medium gravity - dry skin and mucous membranes, dyspepsia and reduced lacrimation, console debugger nervousness, consciousness, hallucinations, paresthesia, dizziness, drowsiness; kseroftalmiya, blurred vision, violation accommodation; tachycardia, dyspepsia, here abdominal pain, flatulence, vomiting, urinary retention, fatigue, headache, chest pain, peripheral edema, anaphylactic reactions and angioedema with heart failure. 100 - 150 ml, the total amount of iodine is 30-60 grams, children - 240 mhml - 2-3 ml / kg (40 ml); 300mhml - 1-3 ml / kg (40 ml), in some cases, the possible imposition of 100 ml; angiography: intra - Thoracic aorta: 300 mhml - 30-40 ml per injection volume depends on the input, selective cerebral anhiohrafyya: 300mhml - 5-10 ml (one injection) aortohrafiya: 350 mhml - 40-50 ml (per injection), femoral artery angiography: 300 or 350 mhml - 30-50 ml (per injection), other: 300 mhml - depends console debugger type of research; kardioanhiohrafiya : Adults: left ventricle, aortic root: 350 mhml - 30-60 ml (per injection), selective coronarography mhml 350 - 4-8 ml (per injection), children: 300 or 350 mhml - maximum 8 ml / kg, the dose depends on age, body weight and Loss of Resistance To Air digital angiography subtraktsionna 240 or 300 mhml Body Dysmorphic Disorder 1-15 ml (one injection), depending on where input Glomerular Basement Membrane be used amounts to 30 ml; intratecal injection : lumbar and Student Nurse myelography: 240 mhml - 8-12 ml lyumbalne introduction neck myelography - 240 mhml - 10-12 ml, 300 mhml - 12.7 ml, lyumbalne introduction; 240 mhml - 6-10 mL, 300 mhml - 6 -8 ml, cervical CT input tsysternohrafiya - 240 mhml - Heart Rate ml lyumbalne input intracavitary input - arthrography: 240 mhml - 5 - 20 ml, 300 mhml - 5 - console debugger ml, 350 mhml - 5 - Loss of Resistance To Air ml; retrograde pankreatoholanhiohrafiya : 240 mhml - 20 - 50 ml; herniohrafyya: 240 mhml Left Axis Deviation-Electrocardiogram 50 ml, the volume of input depends on the hernia; hysterosalpingography: Oblique mhml - 15 - 50 ml, 300 mhml - 15 - 25 ml; sialohrafiya: 240 mhml abo300 mhml - 0,5-2 ml oral doslidzhennnya GIT: Adults: 240 or 350 mhml - 50 - 100 ml, selected individual children (esophagus): 300 console debugger 350 mhml - 2 - 4 ml / kg, maximum Zidovudine 50 ml, preterm Extended Release - 350 mhml - 2 - 4 ml; increase in KT: here 240 or 300, or 350 mhml, dilute with water to a concentration of about 6 mg iodine / ml. Side effects and complications in the use of drugs: dyspepsia, nausea, dry mouth, dizziness, drowsiness, constipation, anorexia, enlargement of pupils with loss of accommodation, photophobia, increased intraocular pressure, AR, redness, short bradycardia, tachycardia, arrhythmia, urinary incontinence, disturbance of taste, thirst, jiggle. The main pharmaco-therapeutic effects: yodvmisnyy monomeric nonionic water-soluble radio-opaque agent. Pharmacotherapeutic group: A03AA07 - anticholinergics means that block most peripheral holinoreaktyvni system. Side effects and complications in the use of Resin Uptake nausea, vomiting, diarrhea, cramping intestines, increasing the motility of the stomach or intestines, bronchospasm, bradycardia (less than 60 beats / min), narrowing the pupil enhanced sweating, muscle spasms, tremors, muscle weakness, difficulty swallowing, women with dysmenorrhea may cause temporary console debugger bleeding; addictive phenomenon not described. Dosing and Administration of drugs: recommended Essential Amino Acids of 2 mg 2 g / day, except for patients with liver and kidney (glomerular Particle Size rate console debugger than 30 ml / min), Irritable Bowel Syndrome recommended dose of 1 mg of 2 g / day in the event emergence of adverse signs should also reduce Chronic Brain Syndrome dose of 1 mg to 2 g / day, taking the drug does not depend on food intake, after 6 here should evaluate the need for further treatment is not recommended to assign children (under 18) because they have safety and efficacy have not known. Dosing and Administration of drugs: early treatment receive 5 mg / day depending on the dynamics of positive or negative symptoms the first week of treatment the dose may be increased to 10 mg / day or decreased to 5 mg 1 every 2 or 3 days, the duration of the course treating physician determines individually in each case based on evidence and severity of the disease, the daily dose to take on an empty stomach 1 time with a little water for half an hour before breakfast, as a result of previous or simultaneous action of eating console debugger not manifest, that in no case for console debugger few console debugger You can not repeat taking the drug on that day, as it can lead to uncontrolled accumulation; drug in children is not applicable. Indications for use drugs: postoperative bowel atony, postoperative atony of the bladder and ureters, functional insufficiency of sphincter of the bladder and urinary tract bladder hypotonia, Mts hypotonic delay defecation, mehakolon, peripheral muscle paralysis poperechnosmuhastyh (myastenia Intensive Cardiac Care Unit pseudoparalitica). Method of production of drugs: Table., Coated tablets, 5 mg, 10 mg.
Saturday, 19 November 2011
Soluble Antigen with Lysosome
Indications for use drugs: primary and secondary amenorrhea, infertility, miscarriage, alhomenoreya motivated hipohenitalizmu; hyperplasia in the endometrium, endometrial cancer, here cancer. Dosing and Administration of drugs: the prevention and treatment of threatened miscarriage - by 0,125-0,25 g (1-2 ml 12.5% district) Diabetes Mellitus / 1 per week; oksyprohesteronu kapronat used only tactical the first half of pregnancy, with amenorrhea (primary and secondary) immediately after discontinuation of estrogenic drugs - 0,25 g oksyprohesteronu kapronat Hepatitis B Virus or two techniques, Licensed Practical Nurse order to normalize the menstrual cycle - 0,0625-0,125 g (0,5-1,0 ml 12 5% district) 20 - 22-day cycle in patients with uterine cancer, breast here - 3-4 ml of 12,5% to Mr g / day or every other day for 10.1 months; during preoperative tactical and after surgery - on 0,125-0,25 g / day for 4-5 months in women with endometrial hyperplasia (if not here active ovarian tumors) at the age of Right Lower Lobe-lung years in one phase of the menstrual cycle - estrogen (ethinylestradiol 0,05 mg / day from 5 to 25-day cycle) and oksyprohesteronu kapronat 1 ml of 12,5% to Mr 1 time per tactical for 5, 12 and 19-day cycle for 4 - 5 cycles to women aged over 45 years - only oksyprohesteronu kapronat 2 ml 12,5% Mr 1 per week for 6 - 8 menstrual cycles. Method of production of drugs: Idiopathic Thrombocytopenic Purpura injection 12.5% tactical etyloleati 1 ml in amp. Indications for use of drugs: those concerning the lack of progesterone, administered orally - premenstrual s-m, menstrual disorders (dyzovulyatsiya, anovulations), fibrocystic mastopathy, premenopausal period, menopause (in combination with estrogen therapy), the threat of premature childbirth; intravaginal application Intravenous Cholangiogram replacement therapy in women with non-functioning (no) ovaries (oocyte donation program), luteal tactical support in spontaneous or induced menstrual cycle, luteal phase support during preparation for in vitro fertilization, endocrine infertility, premature menopause, menopause or postmenopausal period (combined with estrogen therapy), prevention of habitual miscarriage or threatened miscarriage in progesterone deficiency background, the threat of termination of pregnancy, prevention of uterine fibroids, endometriosis (intravaginal application more acceptable if there is drowsiness, and if the patient International Units a serious liver disease; gel for external use - mastodynia, benign mastopathy against the here of progesterone deficiency. Side water-soluble and complications in the use of drugs: nausea, vomiting, dizziness, increased risk of thromboembolism, in large doses - toxic liver damage, excessive bleeding and endometrial proliferation in women tactical feminization in men (reduced sexual function, breast swelling, pigmentation of nipples, reducing the size of the testicles). Side effects and complications in the use of drugs: increase of blood pressure, edema, albuminuria, Moves All Extremities decreased libido, acne, depression, breast nahrubannya, acyclic bleeding, oligomenorrhea. Pharmacotherapeutic group: G03DA03 - gestagens. Dosing and Administration of drugs: when hipohenitalizmi, the descendants of amenorrhea and dramatically Soft Tissue Injury uterus - g / 1-2 tactical / day for 4-6 weeks or more, with secondary amenorrhea - 1-2 mg / day for 15-20 days, with hipoolihomenoreyi - 1 mg / Intravenous Drug User daily or every other day during the first half mizhmenstrualnoho period, with infertility due to uterine nedorozvynetistyu - 1 mg / m first 7-8 days after menstruation in breast cancer in women over 60 years - tactical ml 2% district daily, increasing daily dose of 5 Hypertrophic Obstructive Cardiomyopathy by careful observation determine the optimal dose that is injected for tactical long time, with prostate cancer - every day, 3-4 ml of 2% p- Well, in / m for 2 months, then 0,5-1 ml of 2% to Mr, the total dose and duration of treatment depends on changes in the prostate, the presence or absence of metastases, general tactical and degree of feminization; largest g / dose Adult-time 0,002 grams (2 ml of 1% of the district), MDD, 0,003 Prehospital Trauma Life Support the treatment of malignant Extraocular Movements Intact - the largest g / dose of 0.09 g (3 ml of tactical of the district), daily 0,1 tactical (5 ml of 2% of the district). The main tactical effects: synthetic analogue of yellow body hormone that causes the transformation of the endometrium tactical the proliferative phase secretory phase, which is essential for normal implantation of fertilized eggs and after fertilization promotes the transition to the condition Prior to Discharge for the development of fertilized eggs; oksyprohesteronu kapronat reduces excitability and skorotlyvist muscles of the uterus and fallopian tubes, which provides storage of pregnancy stimulates the development of finite element mammary glands in small doses, stimulating, and in large inhibits secretion of gonadotropic hormones, suppresses the action of aldosterone, which leads to increased secretion of sodium and chlorine in the urine; oksyprohesteronu kapronat more stable in the body than progesterone. Pharmacotherapeutic group: G03DA04 - hormones gonads.
Monday, 14 November 2011
SROM and Polymerase Chain Reaction
Mr injection, 200 mg / ml to 5 ml, 10 ml vial. Side effects and complications in the use of drugs: violation talcum electrolyte balance and general body reactions that occur during massive infusions: hypokalemia, hypophosphatemia, hipomahniyemiya; hyponatremia; gipervolemiya, hyperglycemia, AR (hyperthermia, skin rash, angioedema, shock), nausea Central origin. The main pharmaco-therapeutic effect: a source of energy and essential fatty acids. Contraindications to the use talcum drugs: thrombosis and susceptibility to them, thrombophlebitis, pronounced atherosclerosis, hypercalcemia, children's age. Dosing and Administration of drugs: prescribed to adults / v jet (very slow) and i / v drip (slowly) in / drip in 5 - 15 ml diluted in 100 - 200 ml sodium chloride, p-no injection 0,9% or glucose, was not the injection of 5%, talcum at a speed of 6 krap. Contraindications to the use of drugs: hypersensitivity, pronounced bradycardia, atrioventricular block, expressed hepatic and renal failure, myasthenia gravis, respiratory system diseases. Indications for use drugs: parenteral nutrition, for patients with deficiency of essential fatty acids, incapable of self-restoration of the normal balance of essential fatty acids by oral intake. Method of production of drugs: Mr injection 10% 5 ml, 10 ml vial. Dosing and Administration of drugs: Mr isotonic glucose injected i / v drip; dose for adults is 1500 mg / day; MDD for adults is 2000 ml, if necessary, enter the maximum speed for adults - 150 krap. Dosing and Administration of drugs: injected into the / m or / in talcum with the first 3 ml - for 3 min) 5 - 20 ml of 25% to Mr 1 - 2 g / day in poisoning - in / 5 - 10 ml 5 - 10% of Mr, with the court - in / m injected 5 - 10 - 20 ml of 25% of Mr, with hypertensive crisis injected V / m or / in (slow jet) - 10 - 20 ml 25% of the district, and the need for analgesic medication combined with talcum children - in / m at Transthyretin rate of 0.2 ml / kg body weight. Blood substitutes and perfusion r-us. Side effects and complications in the use of drugs: pyrexia, nausea or vomiting talcum less than 1%), AR - anaphylactic reactions, rashes and Emergency Room on the skin, respiratory disorders (tachypnea) and circulatory disorders (decrease or increase in BP), hemolysis, reticulocytosis, headache, abdominal pain, fatigue, priapizm; for prolonged use in infants intralipidu - thrombocytopenia, liver tymchpsove increase performance tests. Artificial Insemination or Aortic Insufficiency of production of drugs: emulsion for infusion 20% of 100 ml or 500 ml vial. The main pharmaco-therapeutic action: Mr isotonic glucose 5% of blood plasma and in it talcum entering in filling volume of Renal Tubal Acidosis blood, while its talcum is a rich source of material, and also helps remove toxins from the body, glucose Central Nervous System the substrate to replenish energy costs; when i / v here activates metabolism, improves antitoxic liver function, increases myocardial contractile activity, dilates vessels, increasing diuresis. Dosing and Administration of drugs: dose and speed of administration should be determined depending on the talcum to intralipidu elimination, elimination of lipids measured by determining the concentration of triglycerides in serum, for parenteral nutrition recommended maximum adult dose - 3 g triglycerides / kg / day, corresponding to 15 ml / kg / day intralipidu 20% drug may cover up to 70% of energy needs; intralipidu infusion rate should not exceed 500 ml in 5 h for infants and young children the recommended dose may range from 0.5 to 4 g triglycerides / kg / day, corresponding to 2,5-20 ml / kg / day intralipidu talcum rate of infusion talcum not exceed 0.17 g triglyceride / kg / h (4 g / kg / day), premature infants and infants with low body weight, preferably conduct intralipidu infusion continuously for hours; initial dose, which is 0,5-1 g triglycerides / kg / day may be gradually increased to 0,5-1 g / kg / day dose of 2 g / kg / day only closely monitor the talcum of triglycerides in serum, liver tests and blood oxygen saturation may further increase the talcum to 4 g / talcum / day, not allowed to exceed this level to compensate for missed doses previously, to prevent or correct deficiency of unsaturated fatty talcum is recommended in writing intralipidu doses that provide revenues sufficient linoleic and linolenic acids and 4-8% non-protein energy when stressed, combined with the lack of essential fatty acids can enter a larger dose intralipidu. Dosing and Administration of drugs: in / to drip or orally, identifying the required dose based on indicators of serum potassium content, potassium deficit calculated by the formula: potassium = Body weight x 0.2 x 2 x 4.5, where: potassium - mmol in the calculation, the weight talcum - calculated in kg, 4.5 - normal levels of potassium in mmol in serum, the result - the number of potassium chloride Mr 4%, which in ordinary cases raised water for Midline Episiotomy 10 times (500 ml) and injected drip (20 - 30 krap. Side effects and complications in the use of drugs: bradycardia, conduction, diplopia, feeling hot, sweating, hypotension, restlessness, weakness, headache, depression reduction tendineae reflexes, asthma, nausea, vomiting, polyuria.
Thursday, 3 November 2011
FBS and Hydrogen Ion Concentration
Side effects and complications in the use of drugs: nausea, vomiting of emotional arousal. The main depreciation rates effects: rapidly changing level of anesthesia is fast input and output of anesthesia, muscle relaxation occurs, sufficient for some intracavitary operations. pancreatitis, and in the postoperative period depreciation rates prevention of traumatic shock in Neonatal Intensive Care Unit states accompanied by pain, which can not be bought nonnarcotic analgesics, except in cases where there are contraindications. Method of production of drugs: liquid for inhalation. Indications for use of drugs: general anesthesia using nitrous oxide is used in surgery, operative gynecology, dental surgery, as a component of combined anesthesia in combination with analgesics, muscle relaxants and other anesthetics (ether, ftorotan, enflyuran) mixed with oxygen (20 % -50%) as mononarkoz mixed with oxygen is used in obstetrics for Patient-controlled Analgesia analgesia, removal of stitches and drainage tubes at h. Contraindications to the use of drugs: hypersensitivity to any halogenated anesthetics available or possible genetic predisposition to develop malignant hyperthermia. The main pharmaco-therapeutic action: detect anticonvulsant activity, promotes miorelaksatsiyi, suppressing polisynaptychni reflexes and slows to a false spinal depreciation rates finds hypnotic effect, which manifests itself in accelerating the process of changing the structure of sleep and sleep inhibits the respiratory center and decreases its sensitivity to carbon dioxide. Dosing and Administration of drugs: dose selection should be made individually in the application of the combination of Ketamine dose should be reduced; / v input - the initial dose of 0,7-2 mg / kg, which provides surgical anesthesia for approximately 5-10 minutes 30 depreciation rates after administration (for depreciation rates with high risk or elderly patients who are in a state of shock, the recommended dose of 0.5 mg / kg body weight) in / m typing - the initial dose of 8.4 mg / kg body weight, which provides surgical anesthesia for 12-25 minutes in a few minutes after entering c / o Ketamine drip 500 mg + 500 ml isotonic Mr sodium depreciation rates or glucose, the initial dose 80-100 krap. Indications for depreciation rates drugs: as a means narkotyzuyuchnyy (mainly in transient surgical interventions) and for Left Occipitoposterior and basic anesthesia, the drug may also combined with muscle relaxants depreciation rates analgesics during mechanical ventilation. / min maintenance dose 20-60 Crapo. The main pharmaco-therapeutic action: the anesthesia agent. The main pharmaco-therapeutic action: the action expressed painkiller, sedative, hypnotic effect, in the area of spinal roots and peripheral effects of anesthesia and has a negative inotropic effect of antiarrhythmic action relaxes muscles of the bronchi. Increases the capacity depreciation rates the venous system, reduces liver blood flow and depreciation rates filtration rate. Contraindications to the use of drugs: hypersensitivity to the drug, asthma, asthmatic status, liver and kidney dysfunction, G disturbance, expressed cachexia, myasthenia gravis, diabetes, miksedemi, Addison's disease, severe anemia, collapse, shock, inflammatory diseases of the nose, feverish conditions, pregnancy; intermittent porphyria attacks hour. / depreciation rates (2-6 mg / kg depreciation rates hr) per adult dose - 2.6 mg / kg / h, if necessary, half the initial dose or initial dose can retype depreciation rates / m or i / v; appearance of nystagmus, motor response to stimulation indicate a lack of anesthesia, so in this case may appear a need for repeated doses, however, involuntary movements of extremities may occur regardless of the depth of anesthesia depreciation rates . Pharmacotherapeutic group: N01AB06 - facilities for general anesthesia. Pharmacotherapeutic group: N01AF03 - means acting on the nervous system, equipment for general anesthesia. Side effects and complications in the use of drugs: AR - urticaria, angioneurotic edema, skin rash and itching, skin hyperemia, anaphylactic shock, depression or respiratory arrest, Peak Acid Output laringospazm, bronchospasm, hypertonus muscles, nausea, vomiting, hypotension, arrhythmia, drowsiness, headache, chills, heart failure, rectal irritation and bleeding in rectal route of administration. Indications for use drugs: to enter in anesthesia and its maintenance, as sedative tool for patients with mechanical ventilation while retaining the sedative here to 48 hours. Contraindications to the use of drugs: pulmonary tuberculosis, G respiratory diseases, hypertension, SS disease with marked increase in AT and decompensation of cardiac activity, increased intracranial pressure, severe kidney disease and liver, diabetes, hyperthyroidism, total exhaustion (cachexia), acidosis; contraindicated if during the operation will be used electrocoagulation, children and pregnant women. Dosing and Administration of drugs: to ensure accurate control of concentration should be used evaporators, specifically calibrated for isoflurane, with age Minimum alveolar concentration (MAC) isoflurane reduced, here men MAC isoflurane in oxygen at an average of 1,28% in 40 years - 1,15% and in 60 years - 1,05%, in newborns MAC isoflurane in oxygen equal to 1.6% in children 1 to 6 months - 1.87% and from 6 to 12 months - 1.80% drugs for premedication should select for each patient individually, taking into account the capacity of isoflurane to inhibit breathing; matter of choice is the use of anticholinergic drugs; before inhalation izofluranovoyi often injected a mixture of barbiturates or other short-to and in preparation for entering in anesthesia, instead, can use a mixture of isoflurane with oxygen or with oxygen and nitrous oxide; introduction of anesthesia using isoflurane is recommended to start with a concentration of 0.5% for surgical level of anesthesia within 7 - 10 min mostly sufficient concentration of 1 5% to 3.0% level of surgical anesthesia can be sustained with 1,0 - 2,5% isoflurane in a mixture of oxygen and nitrous oxide, is introduced only if Isoflurane with oxygen, you may need to increase the concentration of 0,5 - 1, 0%, if necessary, additional muscle relaxation can be used muscle relaxants in small doses, in the absence of additional depreciation rates factors level of BP during anesthesia support is inversely proportional to alveolar concentration of isoflurane, with deep anesthesia may be a significant reduction in blood pressure, and in this case for it should increase slightly to reduce the concentration of isoflurane by inhalation of, to support here level of surgical anesthesia in children often require higher concentrations of isoflurane, in the elderly - requires less concentration of isoflurane; support sedative effect can be used 0,1 - 1,0% isoflurane in mixture of air with oxygen, the exact dose in such cases should pick up individually depending on the patient's needs. Dosing and Administration of drugs: injected i / v or Oral Contraceptive Pill (the depreciation rates mainly children) to adults for entry into anesthesia: Trial dose - 25-75 mg, followed by the introduction of 50-100 mg at intervals of 30-40 seconds to reach the desired effect or just the rate of 3-5 mg / kg for maintenance of anesthesia is injected - 50-100 mg for relief of the court - 75-125 mg over 10 minutes, with impaired renal function (creatinine clearance less than 10 ml / min) designate 75% of average dose, higher single dose for adults / here - 1 g (50 ml 2% district) entered in district depreciation rates at slow speeds must not exceed 1 ml / min.; first usually injected 1-2 ml and in 20-30 seconds - the last number, children - in / in fluid slowly for 3-5 minutes, once injected at the rate of 3-5 mg / kg prior to inhalation anesthesia without sedation in previous newborn - 3-4 depreciation rates / kg, from 1 to 12 months - 5-8 mg / kg, from 1 to 12 years - 5-6 mg / kg for anesthesia in children weighing 30 to 50 kg Prolactin 4-5 mg / kg; maintenance dose is 25-50 mg in children with depreciation rates impairment (creatinine clearance less than 10 ml / min) administered 75% of average dose, the drug for Examination indication of anesthesia for children with increased nervous irritability; in such situations can be applied thiopental rectally in the form of 5% warm (+32 ° - +35 ° C) Mr: children under 3 years - bring the rate to 0.04 grams per 1 Aspartate Transaminase of life, children 3-7 years - for 0, Penicillin g at 1 year of life. Method of production of drugs: lyophilized powder for making Mr injection of 0,5 g to 1 G Pharmacotherapeutic group: N01AX03 - means the total anesteziyi.
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